Proxidant and antioxidant status in patients of type II Diabetes Mellitus with IHD     

Madhur Gupta  Suresh Chari 《Indian journal of clinical biochemistry : IJCB》2006,21(2):118-122

Patients with type II Diabetes Mellitus (NIDDM) are more prone to Ischaemic Heart Disease (IHD). Although, oxygen free radicals are known to contribute to the development of IHD, conflicting reports are available regarding the antioxidant status in patients of NIDDM complicated with IHD. This study was undertaken to investigate the oxidative status in patients of NIDDM and to assess their correlation with plasma glucose, glycosylated haemoglobin and duration of diabetes. The levels of malondialdehyde were significantly increased where as levels of superoxide dismutase, Glutathione peroxidase and vitamin C were significantly decreased in diabetics without complications and non-diabetics with IHD when compared with the controls. The levels of malondialdehyde and Glutathione peroxidase were significantly increased where as levels of superoxide dismutase and vitamin C were significantly decreased in diabetics with IHD when compared with diabetics without complications and non-diabetics with IHD. The implications of the results are discussed.  相似文献   

eVALUate: an evaluation instrument for measuring students’ perceptions of their engagement and learning outcomes     

Beverley Oliver  Beatrice Tucker  Ritu Gupta  Shelley Yeo 《Assessment & Evaluation in Higher Education》2008,33(6):619-630

In the current climate in Australian higher education, quality assurance in university teaching is a priority. In particular, the introduction of the Learning and Teaching Performance Fund (LTPF) has refocused attention on universities’ internal student evaluation survey instruments. This paper reports the development, validation and implementation of a new unit survey instrument which prompts students to reflect on what helps their achievement of unit learning outcomes, and to report their levels of motivation, engagement and overall satisfaction with a semester‐long course or unit of study. The instrument (eVALUate) was created from precepts reported in the research literature, current practices in evaluating teaching, and sound quality assurance practices appropriate to a university outcomes‐focused education paradigm.  相似文献   

Current Scenario of Prevalence of Vitamin D Deficiency in Ostensibly Healthy Indian Population: A Hospital Based Retrospective Study     

Kirtikar Shukla  Shikha Sharma  Aditi Gupta  Arun Raizada  Kamini Vinayak 《Indian journal of clinical biochemistry : IJCB》2016,31(4):452-457

25-hydroxy vitamin D [25(OH) vit D] deficiency is a serious public health problem, particularly in the Indian sub-continent. The objective of the present study was to study the prevalence of 25(OH) vit D in different age groups. The data of 25(OH) vit D assay of 26,346 ostensibly healthy individuals, enrolled under executive health checkup at Medanta The Medicity, Gurgaon, over a period of 3 years, were extracted from the hospital information system and reviewed extensively. 25(OH) vit D deficiency (VDD) was defined as 25(OH) vit D < 20 ng/ml, insufficiency (VDI) as 25(OH) vit D between 20 and 40 ng/ml and 25(OH) vit D sufficiency (VDS) as 25(OH) D > 40 ng/mL. 25(OH) vit D deficiency (VDD + VDI) was observed in 93 % of the subject population. Maximum number of the subjects belonged to the age group of 41–60 years. 59 % had frank 25(OH) vit D deficiency when cut off level was <20 ng/mL. Mean value of 25(OH) vit D in our subjects was 21.4 ± 14.4 ng/mL. Significant difference in 25(OH) vit D level was observed in between male and female subjects. Simultaneously 25(OH) vit D levels were significantly lower in the patient visited hospital in winter-spring season than the summer-autumn season (p > 0.001). Our study demonstrates a high prevalence of 25(OH) vit D deficiency in an ostensibly healthy Indian population. There is a need for redefining our reference ranges according to our population and extensively improving the status of vitamin D.  相似文献   

Circadian periodicity of plasma lipid peroxides and anti-oxidant enzymes in pulmonary tuberculosis     

Ranjana Singh  Rajesh K. Singh  Anil K. Tripathi  Nikhil Gupta  Ajai Kumar  Anil K. Singh  Abbas A. Mahdi  Rajendra Prasad  Raj K. Singh 《Indian journal of clinical biochemistry : IJCB》2004,19(1):14-20

The circadian periodicity of plasma lipid peroxide levels and activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) were studied in 50 clinically, bacteriologically and radiologically proven fresh cases of pulmonary tuberculosis (age: 21–45 years) and 60 age-matched healthy volunteers with diurnal activity from 06∶00 to about 22∶00 and nocturnal rest. A marked circadian variation in plasma lipid peroxide level was recorded in healthy subjects and pulmonary tuberculosis patients with significant amplitude and acrophase around 16∶21 and 17∶12 respectively. The acrophase tended to be delayed in tuberculosis patients. Furthermore, a statistically significant circadian rhythm was found in SOD, CAT and GPx activities in normal volunteers and pulmonary tuberculopsis patients. SOD and CAT enzyme activity was noted to be maximum at 06∶00 and minimum at 00∶00 in tuberculosis patients. The circadian acrophase for GPx activity was recorded at 16∶15 in normals and around 22∶45 in patients. Moreover, the activity was found to be decreased at all sampling hours during 24-hours sleep-awake period in patients in comparison to healthy counterparts. The MESOR and circadian amplitude also decreased markedly. The decreased activity of measured antioxidant enzymes in pulmonary tuberculosis patients could probably be associated with oxidative stress and/or decreased anti-oxidant defensive mechanism in such patients.  相似文献   

Study of serum lactate dehydrogenase in strangulated and non-strangulated intestinal obstruction     

D. S. Dhiman  N. K. Sarin  R. K. Sharma  J. R. Kanwar  R. M. Pathak  R. L. Gupta 《Indian journal of clinical biochemistry : IJCB》1989,4(1):23-25

The present study has been conducted in 80 cases, out of which 28 were of strangulated and 52 of non-strangulated intestinal obstruction. It has been observed that serum lactate dehydrogenase of more than 300 I. U./litre in first 24 hours to 72 hours is highly suggestive of strangulated intestinal obstruction.  相似文献   

Pathways to understanding mind: construct validity and predictive validity of maternal mind-mindedness   总被引：6，自引：0，他引：6  

Meins E  Fernyhough C  Wainwright R  Clark-Carter D  Das Gupta M  Fradley E  Tuckey M 《Child development》2003,74(4):1194-1211

The construct validity of maternal mind-mindedness (MM) was investigated in the context of its relations with children's later understanding of mind. MM measures were obtained from infant-mother (N = 52) interactions at 6 months, and from maternal interviews at 48 months. Children's understanding of mind was assessed using theory of mind (ToM) tasks at 45 and 48 months, and a stream of consciousness (SoC) task at 55 months. One of the early MM measures--mothers' appropriate mind-related comments--was a positive independent predictor of: (a) MM at 48 months, and (b) ToM and SoC performance at 45 to 55 months. Path analyses suggested direct links between mothers' use of appropriate mind-related comments and children's later understanding of mind.  相似文献   

Enhancing student performance through cooperative learning in physical sciences     

Madan L. Gupta 《Assessment & Evaluation in Higher Education》2004,29(1):63-73

Students in a physical sciences course were introduced to cooperative learning at the University of Queensland, Gatton Campus. Groups of four to five students worked together in tutorial and practical sessions. Mid-term and practical examinations were abolished and 40% of total marks were allocated to the cooperative learning activities. A peer- and self-assessment system was successfully adapted to account for individual performance in cooperative learning group assignments. The results suggest that cooperative learning was very well received by students, and they expressed willingness to join cooperative learning groups in other courses. In addition, cooperative learning offered many benefits to students in terms of graduate attributes such as teamwork, communication, lifelong learning and problem-solving.  相似文献   

BOOK REVIEWS     

Carmen Dalli  Julie Evans  Amita Gupta  Denise Hevey  Rona Tutt OBE  Rona Tutt OBE 《International Journal of Early Years Education》2007,15(3):311-323

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Singapore Colloquial English and Standard English     

Anthea Fraser Gupta 《Asia Pacific Journal of Education》1989,10(2):33-39

Singapore English can be described as diglossic, that is, most of the proficient adult users of English in Singapore use two grammatically distinct varieties of English: (1) Singapore Colloquial English, which is used with close friends, to children, and informally in general and (2) Standard English, which is used in writing, in formal situations, and is associated with education. Singapore Colloquial English is informally learnt, while the teaching of Standard English is a primary responsibility of the school.

Students at the National University of Singapore, and especially those taking courses in the Department of English Language and Literature, can be expected to show the highest attainment levels in Standard English of those coming from the education system. The oral skills of these students are generally very good, both in comprehension and production. Their control of vocabulary is outstanding. While some students still have problems producing Standard English (especially in the area of tenses) most students make few grammatical errors. However, they do have problems with the organisation of material, report writing, and techniques of argumentation. Students also tend to write in a uniformly journalistic style, having little control over the use of different styles for different types of writing. Awareness of the functions of English in Singapore may help teachers to understand the importance of stylistic appropriacy.  相似文献   

The Case for Dynamic Models of Learners' Ontologies in Physics     

Ayush Gupta  David Hammer  Edward F. Redish 《学习科学杂志》2013,22(3):285-321

We cannot really understand how to create computer support for collaborative learning without first becoming clearer about what we mean by communication, collaboration, and learning. After distinguishing several conceptions of communication, and highlighting transformative communications for learning, I consider how, via broadband telepresence, distributed multimedia learning environments may establish such communications by adequately acknowledging the social and material embeddedness of everyday communication. I then describe high-priority areas for advancing this agenda: in sociocultural theory, in examining conceptual change by means of conversational analysis, and in technically establishing affordances of tools to sustain and potentially enhance joint activity beyond the here-and-now and the face-to-face.  相似文献